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Structural Basis of the Induced-Fit Mechanism of 1,4-Dihydroxy-2-Naphthoyl Coenzyme A Synthase from the Crotonase Fold Superfamily

1, 4-Dihydroxy-2-naphthoyl coenzyme A (DHNA-CoA) synthase is a typical crotonase fold enzyme with an implicated role of conformational changes in catalysis. We have identified these conformational changes by determining the structures of its Escherichia coli and Synechocystis sp. PCC6803 orthologues...

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Autors principals: Sun, Yueru, Song, Haigang, Li, Jie, Li, Yan, Jiang, Ming, Zhou, Jiahai, Guo, Zhihong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637252/
https://ncbi.nlm.nih.gov/pubmed/23658663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063095
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