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Structure of Staphylococcus aureus 1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA

Vitamin K(2), or menaquinone, is an essential cofactor for many organisms and the enzymes involved in its biosynthesis are potential antimicrobial drug targets. One of these enzymes, 1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) from the pathogen Staphylococcus aureus, has been obtained in recombina...

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Detalhes bibliográficos
Main Authors: Ulaganathan, Venkatasubramanian, Agacan, Mark F., Buetow, Lori, Tulloch, Lindsay B., Hunter, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2339762/
https://ncbi.nlm.nih.gov/pubmed/18007038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107047720
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