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Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae

Efficient production of sesquiterpenes in Saccharomyces cerevisiae requires a high flux through the mevalonate pathway. To achieve this, the supply of acetyl-CoA plays a crucial role, partially because nine moles of acetyl-CoA are necessary to produce one mole of farnesyl diphosphate, but also to ov...

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Dettagli Bibliografici
Pubblicato in:J Ind Microbiol Biotechnol
Autori principali: Tippmann, Stefan, Ferreira, Raphael, Siewers, Verena, Nielsen, Jens, Chen, Yun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432608/
https://ncbi.nlm.nih.gov/pubmed/28185100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-017-1911-6
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