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Production of N-acetylgalactosaminyl-transferase 2 (GalNAc-T2) fused with secretory signal Igκ in insect cells

The human UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase 2 (GalNAc-T2) is one of the key enzymes that initiate synthesis of hinge-region O-linked glycans of human immunoglobulin A1 (IgA1). We designed secreted soluble form of human GalNAc-T2 as a fusion protein contain...

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Autori principali: Horynová, Milada, Takahashi, Kazuo, Hall, Stacy, Renfrow, Matthew B., Novak, Jan, Raška, Milan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637031/
https://ncbi.nlm.nih.gov/pubmed/22033505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2011.10.006
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