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IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

GalNAc-type O-glycans are often added to proteins post-translationally in a clustered manner in repeat regions of proteins, such as mucins and IgA1. Observed IgA1 glycosylation patterns show that glycans occur at similar sites with similar structures. It is not clear how the sites and number of glyc...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Stewart, Tyler J, Takahashi, Kazuo, Whitaker, Robert H, Raska, Milan, Placzek, William J, Novak, Jan, Renfrow, Matthew B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583770/
https://ncbi.nlm.nih.gov/pubmed/30759204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz007
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