IgA1 hinge-region clustered glycan fidelity is established early during semi-ordered glycosylation by GalNAc-T2

GalNAc-type O-glycans are often added to proteins post-translationally in a clustered manner in repeat regions of proteins, such as mucins and IgA1. Observed IgA1 glycosylation patterns show that glycans occur at similar sites with similar structures. It is not clear how the sites and number of glyc...

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Publicat a:Glycobiology
Autors principals: Stewart, Tyler J, Takahashi, Kazuo, Whitaker, Robert H, Raska, Milan, Placzek, William J, Novak, Jan, Renfrow, Matthew B
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Regular Manuscripts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583770/
https://ncbi.nlm.nih.gov/pubmed/30759204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz007
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