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Epithelial Cell Adhesion Molecule (EpCAM) Regulates Claudin Dynamics and Tight Junctions

Epithelial cell adhesion molecule (EpCAM) (CD326) is a surface glycoprotein expressed by invasive carcinomas and some epithelia. Herein, we report that EpCAM regulates the composition and function of tight junctions (TJ). EpCAM accumulated on the lateral interfaces of human colon carcinoma and norma...

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Autori principali: Wu, Chuan-Jin, Mannan, Poonam, Lu, Michael, Udey, Mark C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636909/
https://ncbi.nlm.nih.gov/pubmed/23486470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.457499
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