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Epithelial Cell Adhesion Molecule (EpCAM) Regulates Claudin Dynamics and Tight Junctions

Epithelial cell adhesion molecule (EpCAM) (CD326) is a surface glycoprotein expressed by invasive carcinomas and some epithelia. Herein, we report that EpCAM regulates the composition and function of tight junctions (TJ). EpCAM accumulated on the lateral interfaces of human colon carcinoma and norma...

詳細記述

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書誌詳細
主要な著者: Wu, Chuan-Jin, Mannan, Poonam, Lu, Michael, Udey, Mark C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636909/
https://ncbi.nlm.nih.gov/pubmed/23486470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.457499
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