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Genetic Deletion of Catalytic Subunits of AMP-activated Protein Kinase Increases Osteoclasts and Reduces Bone Mass in Young Adult Mice

AMP-activated protein kinase (AMPK) is a key regulator of cellular and systemic energy homeostasis and a potential therapeutic target for the intervention of cancer and metabolic disorders. However, the role of AMPK in bone homeostasis remains incompletely understood. Here we assessed the skeletal p...

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Detalhes bibliográficos
Main Authors: Kang, Heeseog, Viollet, Benoit, Wu, Dianqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636902/
https://ncbi.nlm.nih.gov/pubmed/23486478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430389
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