Shedding of Discoidin Domain Receptor 1 by Membrane-type Matrix Metalloproteinases

The discoidin domain receptors (DDRs) are receptor tyrosine kinases that upon binding to collagens undergo receptor phosphorylation, which in turn activates signal transduction pathways that regulate cell-collagen interactions. We report here that collagen-dependent DDR1 activation is partly regulat...

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Detalhes bibliográficos
Main Authors: Fu, Hsueh-Liang, Sohail, Anjum, Valiathan, Rajeshwari R., Wasinski, Benjamin D., Kumarasiri, Malika, Mahasenan, Kiran V., Bernardo, M. Margarida, Tokmina-Roszyk, Dorota, Fields, Gregg B., Mobashery, Shahriar, Fridman, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636896/
https://ncbi.nlm.nih.gov/pubmed/23519472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409599
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