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β-Cell–Specific Protein Kinase A Activation Enhances the Efficiency of Glucose Control by Increasing Acute-Phase Insulin Secretion

Acute insulin secretion determines the efficiency of glucose clearance. Moreover, impaired acute insulin release is characteristic of reduced glucose control in the prediabetic state. Incretin hormones, which increase β-cell cAMP, restore acute-phase insulin secretion and improve glucose control. To...

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Detalhes bibliográficos
Main Authors: Kaihara, Kelly A., Dickson, Lorna M., Jacobson, David A., Tamarina, Natalia, Roe, Michael W., Philipson, Louis H., Wicksteed, Barton
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636652/
https://ncbi.nlm.nih.gov/pubmed/23349500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1013
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