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Long-term activation of PKA in β-cells provides sustained improvement to glucose control, insulin sensitivity and body weight
Type 2 diabetes is associated with obesity, insulin resistance and β-cell failure. Therapeutic aims are to reduce adiposity, improve insulin sensitivity and enhance β-cell function. However, it has been proposed that chronically increasing insulin release leads to β-cell exhaustion and failure. We p...
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| Publicado no: | Islets |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5029204/ https://ncbi.nlm.nih.gov/pubmed/27340937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2016.1198457 |
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