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Saccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere Shortening

In many somatic human tissues, telomeres shorten progressively because of the DNA-end replication problem. Consequently, cells cease to proliferate and are maintained in a metabolically viable state called replicative senescence. These cells are characterized by an activation of DNA damage checkpoin...

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Bibliografski detalji
Glavni autor: Teixeira, M. Teresa
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636481/
https://ncbi.nlm.nih.gov/pubmed/23638436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00101
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