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The asymmetry of telomere replication contributes to replicative senescence heterogeneity
In eukaryotes, the absence of telomerase results in telomere shortening, eventually leading to replicative senescence, an arrested state that prevents further cell divisions. While replicative senescence is mainly controlled by telomere length, the heterogeneity of its onset is not well understood....
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606794/ https://ncbi.nlm.nih.gov/pubmed/26468778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15326 |
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