Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells

Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through Proliferator Activator Receptor (PPARα) -dependent d...

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Autori principali: Mulay, Vishwaroop, Wood, Peta, Manetsch, Melanie, Darabi, Masoud, Cairns, Rose, Hoque, Monira, Chan, Karen Cecilia, Reverter, Meritxell, Álvarez-Guaita, Anna, Rye, Kerry-Anne, Rentero, Carles, Heeren, Joerg, Enrich, Carlos, Grewal, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636258/
https://ncbi.nlm.nih.gov/pubmed/23634230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062667
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