Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells

Signal transduction modulates expression and activity of cholesterol transporters. We recently demonstrated that the Ras/mitogen-activated protein kinase (MAPK) signaling cascade regulates protein stability of Scavenger Receptor BI (SR-BI) through Proliferator Activator Receptor (PPARα) -dependent d...

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Bibliographic Details
Main Authors: Mulay, Vishwaroop, Wood, Peta, Manetsch, Melanie, Darabi, Masoud, Cairns, Rose, Hoque, Monira, Chan, Karen Cecilia, Reverter, Meritxell, Álvarez-Guaita, Anna, Rye, Kerry-Anne, Rentero, Carles, Heeren, Joerg, Enrich, Carlos, Grewal, Thomas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636258/
https://ncbi.nlm.nih.gov/pubmed/23634230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062667
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