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Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants
The PTEN-induced kinase 1 (PINK1) is a mitochondrial kinase, and pink1 mutations cause early onset Parkinson's disease (PD) in humans. Loss of pink1 in Drosophila leads to defects in mitochondrial function, and genetic data suggest that another PD-related gene product, Parkin, acts with pink1 t...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636082/ https://ncbi.nlm.nih.gov/pubmed/23637640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003478 |
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