The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

Pink1 is a mitochondrial kinase involved in Parkinson's disease, and loss of Pink1 function affects mitochondrial morphology via a pathway involving Parkin and components of the mitochondrial remodeling machinery. Pink1 loss also affects the enzymatic activity of isolated Complex I of the elect...

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Autores principales: Vilain, Sven, Esposito, Giovanni, Haddad, Dominik, Schaap, Onno, Dobreva, Mariya P., Vos, Melissa, Van Meensel, Stefanie, Morais, Vanessa A., De Strooper, Bart, Verstreken, Patrik
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252300/
https://ncbi.nlm.nih.gov/pubmed/22242018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002456
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