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HCV-Induced miR-21 Contributes to Evasion of Host Immune System by Targeting MyD88 and IRAK1

Upon recognition of viral components by pattern recognition receptors, such as the toll-like receptors (TLRs) and retinoic acid-inducible gene I (RIG-I)-like helicases, cells are activated to produce type I interferon (IFN) and proinflammatory cytokines. These pathways are tightly regulated by the h...

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Detalhes bibliográficos
Main Authors: Chen, Yanni, Chen, Junbo, Wang, Hui, Shi, Jingjing, Wu, Kailang, Liu, Shi, Liu, Yingle, Wu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635988/
https://ncbi.nlm.nih.gov/pubmed/23633945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003248
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