High EGFR copy number predicts benefits from tyrosine kinase inhibitor treatment for non-small cell lung cancer patients with wild-type EGFR

BACKGROUND: This study was designed to determine whether advanced non-small-cell lung cancer (NSCLC) patients with high copy number of epidermal growth factor receptor (EGFR) can benefit from treatment with EGFR-tyrosine kinase inhibitors (TKIs). METHODS: EGFR gene copy number was assessed by fluore...

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Detalhes bibliográficos
Main Authors: Wang, Fang, Fu, Sha, Shao, Qiong, Zhou, Yan-Bin, Zhang, Xiao, Zhang, Xu, Xue, Cong, Lin, Jian-Guang, Huang, Li-Xia, Zhang, Li, Zhang, Wei-Min, Shao, Jian-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635875/
https://ncbi.nlm.nih.gov/pubmed/23557218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-90
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