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Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways

Autoimmunity is the consequence of the combination of genetic predisposition and environmental effects, such as infection, injury, and constitution of the gut microbiome. In this edition of the JCI, Dai et al. describe the use of knockin technology to test the mechanism of action of a polymorphism i...

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Hlavní autor: Cambier, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635745/
https://ncbi.nlm.nih.gov/pubmed/23619359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69289
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