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Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways
Autoimmunity is the consequence of the combination of genetic predisposition and environmental effects, such as infection, injury, and constitution of the gut microbiome. In this edition of the JCI, Dai et al. describe the use of knockin technology to test the mechanism of action of a polymorphism i...
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Formato: | Artigo |
Idioma: | Inglês |
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American Society for Clinical Investigation
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635745/ https://ncbi.nlm.nih.gov/pubmed/23619359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69289 |
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