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A “hotspot” for autoimmune T cells in type 1 diabetes

The ability of a single T cell antigen receptor (TCR) to cross-react with multiple antigens allows the finite number of T cells within an organism to respond to the compendium of pathogen challenges faced during a lifetime. Effective immune surveillance, however, comes at a price. TCR cross-reactivi...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Stadinski, Brian D., Obst, Reinhard, Huseby, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887178/
https://ncbi.nlm.nih.gov/pubmed/27183386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88165
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