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The relationship between Sonic hedgehog signalling, cilia and neural tube defects
The Hedgehog signalling pathway is essential for many aspects of normal embryonic development, including formation and patterning of the neural tube. Absence of Shh ligand is associated with the midline defect holoprosencephaly, while increased Shh signalling is associated with exencephaly and spina...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635124/ https://ncbi.nlm.nih.gov/pubmed/20544799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20686 |
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