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Comparison of N-acetylmethionine reactivity between oxaliplatin and an oxaliplatin derivative with chiral (S,S) amine nitrogen atoms
We have synthesized an oxaliplatin derivative using N,N′-dimethyl-1,2-diaminocyclohexane (Me(2)dach) as the diamine ligand. The complex (S,R,R,S)-Pt(Me(2)dach)(oxalate), where S,R,R,S represents the chiralities at N,C,C,N, respectively, was prepared and characterized by (1)H NMR spectroscopy, COSY,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635081/ https://ncbi.nlm.nih.gov/pubmed/23626375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ica.2013.03.008 |
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