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NLRP1 dependent pyroptosis leads to acute lung injury and morbidity in mice

Acute inflammation in response to both exogenous and endogenous danger signals can lead to the assembly of cytoplasmic inflammasomes that stimulate the activation of caspase-1. Subsequently, caspase-1 facilitates the maturation and release of cytokines and also, under some circumstances, the inducti...

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Bibliographische Detailangaben
Hauptverfasser: Kovarova, Martina, Hesker, Pamela R., Jania, Leigh, Nguyen, MyTrang, Snouwaert, John N., Xiang, Zhidan, Lommatzsch, Stephen E., Huang, Max T., Ting, Jenny P.-Y., Koller, Beverly H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635067/
https://ncbi.nlm.nih.gov/pubmed/22753929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201065
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