NLRP1 dependent pyroptosis leads to acute lung injury and morbidity in mice

Acute inflammation in response to both exogenous and endogenous danger signals can lead to the assembly of cytoplasmic inflammasomes that stimulate the activation of caspase-1. Subsequently, caspase-1 facilitates the maturation and release of cytokines and also, under some circumstances, the inducti...

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Main Authors: Kovarova, Martina, Hesker, Pamela R., Jania, Leigh, Nguyen, MyTrang, Snouwaert, John N., Xiang, Zhidan, Lommatzsch, Stephen E., Huang, Max T., Ting, Jenny P.-Y., Koller, Beverly H.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635067/
https://ncbi.nlm.nih.gov/pubmed/22753929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201065
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