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PGE(2) through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth
The ductus arteriosus (DA) is a fetal shunt that directs right ventricular outflow away from pulmonary circulation and into the aorta. Critical roles for prostaglandin E(2) (PGE(2)) and the EP4 receptor (EP4) have been established in maintaining both the patency of the vessel in utero and in its clo...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312001/ https://ncbi.nlm.nih.gov/pubmed/22342504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2012.02.001 |
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