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PGE(2) through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth

The ductus arteriosus (DA) is a fetal shunt that directs right ventricular outflow away from pulmonary circulation and into the aorta. Critical roles for prostaglandin E(2) (PGE(2)) and the EP4 receptor (EP4) have been established in maintaining both the patency of the vessel in utero and in its clo...

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Detalles Bibliográficos
Main Authors: Gruzdev, Artiom, Nguyen, MyTrang, Kovarova, Martina, Koller, Beverly H.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312001/
https://ncbi.nlm.nih.gov/pubmed/22342504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2012.02.001
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