PGE(2) Promotes Apoptosis Induced by Cytokine Deprivation through EP3 Receptor and Induces Bim in Mouse Mast Cells

Increased mast cell numbers are observed at sites of allergic inflammation and restoration of normal mast cell numbers is critical to the resolution of these responses. Early studies showed that cytokines protect mast cells from apoptosis, suggesting a simple model in which diminished cytokine level...

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Bibliographic Details
Main Authors: Kovarova, Martina, Koller, Beverly H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108439/
https://ncbi.nlm.nih.gov/pubmed/25054560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102948
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