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Dabigatran Does Not Prolong the QT Interval with Supratherapeutic Exposure: a Thorough QT Study in Healthy Subjects
BACKGROUND: Dabigatran etexilate is a pro-drug of the oral reversible direct thrombin inhibitor dabigatran that interacts with the active site in the catalytic domain of the thrombin molecule. OBJECTIVE: To assess the electrophysiological effects of therapeutic and supratherapeutic doses of dabigatr...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer International Publishing AG
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634983/ https://ncbi.nlm.nih.gov/pubmed/23519576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40261-013-0058-0 |
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