EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism

Lignende værker

• Agonistic antibodies stimulate the kinase encoded by the neu protooncogene in living cells but the oncogenic mutant is constitutively active.
  af: Yarden, Y
  Udgivet: (1990)
• Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy
  af: Pines, Gur, et al.
  Udgivet: (2010)
• Crystal Structure of Arabidopsis Cyclophilin38 Reveals a Previously Uncharacterized Immunophilin Fold and a Possible Autoinhibitory Mechanism([W])
  af: Vasudevan, Dileep, et al.
  Udgivet: (2012)
• LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII
  af: Stutz, MA, et al.
  Udgivet: (2008)
• Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation
  af: Kancha, Rama Krishna, et al.
  Udgivet: (2013)