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Expression and functional characterization of natural R147W and K150del variants of protein C in the Chinese population
Protein C is a vitamin K-dependent serine protease zymogen in plasma which upon activation to activated protein C (APC) by thrombin down-regulates the clotting cascade by limited proteolysis of the procoagulant cofactors Va and VIIIa. In addition to its anticoagulant activity, APC also exhibits pote...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3634890/ https://ncbi.nlm.nih.gov/pubmed/23389250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-10-0760 |
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