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Chaperone-independent mitochondrial translocation and protection by αB-crystallin in RPE cells

αB-crystallin is a small heat shock protein that exhibits chaperone activity and can protect multiple cell types against oxidative stress damage. Altered levels and specific mutations of αB-crystallin are associated with multiple degenerative diseases. We previously found that αB-crystallin transloc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McGreal, Rebecca S, Brennan, Lisa A, Kantorow, Wanda Lee, Wilcox, Jeffrey D, Wei, Jianning, Chauss, Daniel, Kantorow, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634887/
https://ncbi.nlm.nih.gov/pubmed/23466869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.02.016
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