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Promoter-enhancer looping and shadow enhancers of the mouse αA-crystallin locus

Gene regulation by enhancers is important for precise temporal and spatial gene expression. Enhancers can drive gene expression regardless of their location, orientation or distance from the promoter. Changes in chromatin conformation and chromatin looping occur to bring the promoter and enhancers i...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: McGreal-Estrada, Rebecca S., Wolf, Louise V., Cvekl, Ales
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310886/
https://ncbi.nlm.nih.gov/pubmed/30404901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.036897
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