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Methionine Sulfoxide Reductase A (MsrA) restores α-crystallin chaperone activity lost upon methionine oxidation

BACKGROUND: Lens cataract is associated with protein oxidation and aggregation. Two proteins that cause cataract when deleted from the lens are methionine sulfoxide reductase A (MsrA) that repairs protein methionine sulfoxide (PMSO) oxidized proteins and α-crystallin which is a two subunit (αA and α...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Brennan, Lisa A, Lee, Wanda, Giblin, Frank J, David, Larry L, Kantorow, Marc
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783866/
https://ncbi.nlm.nih.gov/pubmed/19733220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.08.011
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