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Methionine Sulfoxide Reductase A (MsrA) restores α-crystallin chaperone activity lost upon methionine oxidation
BACKGROUND: Lens cataract is associated with protein oxidation and aggregation. Two proteins that cause cataract when deleted from the lens are methionine sulfoxide reductase A (MsrA) that repairs protein methionine sulfoxide (PMSO) oxidized proteins and α-crystallin which is a two subunit (αA and α...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783866/ https://ncbi.nlm.nih.gov/pubmed/19733220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.08.011 |
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