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Genetic Variants and Increased Expression of Parascaris equorum P-glycoprotein-11 in Populations with Decreased Ivermectin Susceptibility

Macrocyclic lactones (MLs) represent the major drug class for control of parasitic infections in humans and animals. However, recently reports of treatment failures became more frequent. In addition to human and ruminant parasitic nematodes this also is the case for the horse-nematode Parascaris equ...

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Détails bibliographiques
Auteurs principaux: Janssen, I. Jana I., Krücken, Jürgen, Demeler, Janina, Basiaga, Marta, Kornaś, Sławomir, von Samson-Himmelstjerna, Georg
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634834/
https://ncbi.nlm.nih.gov/pubmed/23637871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061635
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