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Transgenically expressed Parascaris P-glycoprotein-11 can modulate ivermectin susceptibility in Caenorhabditis elegans

P-glycoproteins (Pgps) are suspected to mediate drug extrusion in nematodes contributing to macrocyclic lactone resistance. This association was recently shown for Parascaris Pgp-11. Ivermectin resistance was correlated with the presence of three pgp-11 single nucleotide polymorphisms and/or increas...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Parasitol Drugs Drug Resist
मुख्य लेखकों: Janssen, I. Jana I., Krücken, Jürgen, Demeler, Janina, von Samson-Himmelstjerna, Georg
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401813/
https://ncbi.nlm.nih.gov/pubmed/25905032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.03.003
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