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Genetic Variants and Increased Expression of Parascaris equorum P-glycoprotein-11 in Populations with Decreased Ivermectin Susceptibility

Macrocyclic lactones (MLs) represent the major drug class for control of parasitic infections in humans and animals. However, recently reports of treatment failures became more frequent. In addition to human and ruminant parasitic nematodes this also is the case for the horse-nematode Parascaris equ...

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Detalhes bibliográficos
Main Authors: Janssen, I. Jana I., Krücken, Jürgen, Demeler, Janina, Basiaga, Marta, Kornaś, Sławomir, von Samson-Himmelstjerna, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634834/
https://ncbi.nlm.nih.gov/pubmed/23637871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061635
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