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Chemical Chaperones Exceed the Chaperone Effects of RIC-3 in Promoting Assembly of Functional α7 AChRs

Functional α7 nicotinic acetylcholine receptors (AChRs) do not assemble efficiently in cells transfected with α7 subunits unless the cells are also transfected with the chaperone protein RIC-3. Despite the presence of RIC-3, large amounts of these subunits remain improperly assembled. Thus, addition...

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Bibliographische Detailangaben
Hauptverfasser: Kuryatov, Alexander, Mukherjee, Jayanta, Lindstrom, Jon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634732/
https://ncbi.nlm.nih.gov/pubmed/23638015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062246
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