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Chemical Chaperones Exceed the Chaperone Effects of RIC-3 in Promoting Assembly of Functional α7 AChRs

Functional α7 nicotinic acetylcholine receptors (AChRs) do not assemble efficiently in cells transfected with α7 subunits unless the cells are also transfected with the chaperone protein RIC-3. Despite the presence of RIC-3, large amounts of these subunits remain improperly assembled. Thus, addition...

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Detalhes bibliográficos
Main Authors: Kuryatov, Alexander, Mukherjee, Jayanta, Lindstrom, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634732/
https://ncbi.nlm.nih.gov/pubmed/23638015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062246
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