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Kinetics and Mechanisms of Oxidative Cleavage of HIV RRE RNA by Rev-Coupled Transition Metal Chelates

Catalytic metallodrugs were used to oxidatively cleave HIV-1 Rev Response Element RNA (RRE RNA), and the mechanisms of RNA cleavage were studied using a combination of matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS), fluorescence spectroscopy, and gel elec...

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Detalhes bibliográficos
Main Authors: Joyner, Jeff C., Keuper, Kevin D., Cowan, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634708/
https://ncbi.nlm.nih.gov/pubmed/23626900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC22135K
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