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Targeted Cleavage of HIV RRE RNA by Rev-Coupled Transition Metal Chelates

A series of compounds that target reactive metal-chelates to the HIV-1 Rev Response Element (RRE) mRNA have been synthesized. Dissociation constants and chemical reactivity toward HIV RRE RNA have been determined and evaluated in terms of reduction potential, coordination unsaturation, and overall c...

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Detalhes bibliográficos
Main Authors: Joyner, Jeff C., Cowan, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387528/
https://ncbi.nlm.nih.gov/pubmed/21585196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja203057z
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