A murine Zic3 transcript with a premature termination codon evades nonsense-mediated decay during axis formation

The ZIC transcription factors are key mediators of embryonic development and ZIC3 is the gene most commonly associated with situs defects (heterotaxy) in humans. Half of patient ZIC3 mutations introduce a premature termination codon (PTC). In vivo, PTC-containing transcripts might be targeted for no...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ahmed, Jehangir N., Ali, Radiya G., Warr, Nicholas, Wilson, Heather M., Bellchambers, Helen M., Barratt, Kristen S., Thompson, Amelia J., Arkell, Ruth M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634658/
https://ncbi.nlm.nih.gov/pubmed/23471918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.011668
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados