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Orexin Gene Transfer into Zona Incerta Neurons Suppresses Muscle Paralysis in Narcoleptic Mice

Cataplexy, a sudden unexpected muscle paralysis, is a debilitating symptom of the neurodegenerative sleep disorder, narcolepsy. During these attacks, the person is paralyzed, but fully conscious and aware of their surroundings. To identify potential neurons that might serve as surrogate orexin neuro...

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Autors principals: Liu, Meng, Blanco-Centurion, Carlos, Konadhode, RodaRani, Begum, Suraiya, Pelluru, Dheeraj, Gerashchenko, Dmitry, Sakurai, Takeshi, Yanagisawa, Masashi, van den Pol, Anthony N., Shiromani, Priyattam J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634582/
https://ncbi.nlm.nih.gov/pubmed/21508228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6069-10.2011
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