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Orexin Gene Transfer into Zona Incerta Neurons Suppresses Muscle Paralysis in Narcoleptic Mice

Cataplexy, a sudden unexpected muscle paralysis, is a debilitating symptom of the neurodegenerative sleep disorder, narcolepsy. During these attacks, the person is paralyzed, but fully conscious and aware of their surroundings. To identify potential neurons that might serve as surrogate orexin neuro...

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Hlavní autoři: Liu, Meng, Blanco-Centurion, Carlos, Konadhode, RodaRani, Begum, Suraiya, Pelluru, Dheeraj, Gerashchenko, Dmitry, Sakurai, Takeshi, Yanagisawa, Masashi, van den Pol, Anthony N., Shiromani, Priyattam J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634582/
https://ncbi.nlm.nih.gov/pubmed/21508228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6069-10.2011
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