Cardiac Na(+)–Ca(2+) exchanger: dynamics of Ca(2+)-dependent activation and deactivation in intact myocytes

Cardiac Na(+)–Ca(2+) exchange (NCX) activity is regulated by [Ca(2+)](i). The physiological role and dynamics of this process in intact cardiomyocytes are largely unknown. We examined NCX Ca(2+) activation in intact rabbit and mouse cardiomyocytes at 37°C. Sarcoplasmic reticulum (SR) function was bl...

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Bibliographic Details
Main Authors: Ginsburg, Kenneth S, Weber, Christopher R, Bers, Donald M
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2013
Subjects:
Molecular and Cellular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634520/
https://ncbi.nlm.nih.gov/pubmed/23401616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.252080
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