Measuring Local Gradients of Intra-Mitochondrial [Ca] in Cardiac Myocytes During SR Ca Release

RATIONALE: Mitochondrial [Ca(2+)] ([Ca(2+)](mito)) regulates mitochondrial energy production, provides transient Ca(2+)buffering under stress and can be involved in cell death. Mitochondria are near the sarcoplasmic reticulum (SR) in cardiac myocytes and evidence for crosstalk exists. However, quant...

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Hlavní autoři: Lu, Xiyuan, Ginsburg, Kenneth S., Kettlewell, Sarah, Bossuyt, Julie, Smith, Godfrey L., Bers, Donald M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566246/
https://ncbi.nlm.nih.gov/pubmed/23243207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.300501
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