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Identification of cancer fusion drivers using network fusion centrality

Summary: Gene fusions are being discovered at an increasing rate using massively parallel sequencing technologies. Prioritization of cancer fusion drivers for validation cannot be performed using traditional single-gene based methods because fusions involve portions of two partner genes. To address...

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Hlavní autoři: Wu, Chia-Chin, Kannan, Kalpana, Lin, Steven, Yen, Laising, Milosavljevic, Aleksandar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634186/
https://ncbi.nlm.nih.gov/pubmed/23505294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt131
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