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Identification of rare cancer driver mutations by network reconstruction

Recent large-scale tumor resequencing studies have identified a number of mutations that might be involved in tumorigenesis. Analysis of the frequency of specific mutations across different tumors has been able to identify some, but not all of the mutated genes that contribute to tumor initiation an...

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Библиографические подробности
Главные авторы: Torkamani, Ali, Schork, Nicholas J.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752121/
https://ncbi.nlm.nih.gov/pubmed/19574499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.092833.109
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