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On the Power and the Systematic Biases of the Detection of Chromosomal Inversions by Paired-End Genome Sequencing

One of the most used techniques to study structural variation at a genome level is paired-end mapping (PEM). PEM has the advantage of being able to detect balanced events, such as inversions and translocations. However, inversions are still quite difficult to predict reliably, especially from high-t...

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Detalhes bibliográficos
Main Authors: Lucas Lledó, José Ignacio, Cáceres, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634047/
https://ncbi.nlm.nih.gov/pubmed/23637806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061292
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