Severe Liver Cirrhosis Markedly Reduces AhR-Mediated Induction of Cytochrome P450 in Rats by Decreasing the Transcription of Target Genes

Although the induction of cytochrome P450 (CYP) has long been investigated in patients with cirrhosis, the question whether liver dysfunction impairs the response to CYP inducers still remains unresolved. Moreover, the mechanism underlying the possible effect of cirrhosis on induction has not been i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Floreani, Maura, De Martin, Sara, Gabbia, Daniela, Barbierato, Massimo, Nassi, Alberto, Mescoli, Claudia, Orlando, Rocco, Bova, Sergio, Angeli, Paolo, Gola, Elisabetta, Sticca, Antonietta, Palatini, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633963/
https://ncbi.nlm.nih.gov/pubmed/23626760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061983
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados